Prof.Dr. HAN-YONG BAE
Associate Professor
(배한용, 裵漢容)
ORCID: 0000-0002-7559-7919
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Linkedin
#330616 Chemistry Building
Department of Chemistry, SKKU
2066, Seobu-ro, Jangan-gu, Suwon-si
Republic of Korea 16419
E-mail: hybae@skku.edu
Tel: +82 31 290 7062
HAN-YONG BAE was born in Daegu, Republic of Korea. He received his B.Sc. (2010), M.Sc. (2012) and Ph.D. (2015) degrees from
SUNGKYUNKWAN UNIVERSITY (SKKU, Korea), conducting studies
on Brønsted base catalyzed asymmetric catalysis under the supervision of Professor Choong Eui Song. During his graduate studies, Han-Yong developed polyketide biosynthesis mimic asymmetric organocatalysis and discovered hydrophobic amplification effect in water promoted asymmetric catalysis.
After completion of his graduate studies, he moved to Germany and pursued postdoctoral research with Professor Benjamin List (Nobel Prize in Chemistry 2021) at MAX-PLANCK-INSTITUT FÜR KOHLENFORSCHUNG. He developed new highly active chiral catalysts for extremely challenging Lewis acid-catalyzed asymmetric reactions (parts-per-billion-level organocatalysis).
In 2019, Han-Yong was appointed as an Assistant Professor at Ulsan National Institute of Science and Technology (UNIST, Korea), then came back to
SKKU as an Assistant Professor.
PROFESSIONAL EXPERIENCE & EMPLOYMENT
SKKU, Korea
Associate Professor (tenure track)
2024 – present
SKKU, Korea
Assistant Professor (tenure track)
2019 – 2024
UNIST, Korea
Assistant Professor (tenure track)
2019 – 2019
Max-Planck-Institut für Kohlenforschung, Germany
Scientist/ Postdoctoral researcher (with Professor Benjamin List)
2015 – 2019
Korean Army
Discharged as Sergeant, The 50th Infantry Division
2005 – 2007
EDUCATION
SKKU, Korea
Ph.D. Organic Chemistry, 2015
• Advisor: Professor Choong Eui Song
• Thesis title: Bio-inspired Hydrogen Bonding Promoted Asymmetric Organocatalysis [Download full-thesis]
SKKU, Korea
B. Sc. Chemistry, 2010/ M.Sc. Chemistry, 2012
• Advisor: Professor Choong Eui Song
• Thesis title: Biomimetic Enantioselective Organocatalysis
SELECTED AWARDS, HONORS & SCHOLARSHIPS
• SKKU Faculty Performance Achievement (2024, Research 신품(神品))
• SKKU Faculty Performance Achievement (2024, Education 묘품(妙品))
• Korea Toray Fellowship, Oct 2024
• Best Teacher Award - Outstanding Lecture Portfolio, SKKU, Dec 2023
• Young Advisory Board Member of the Bulletin of the Korean Chemical Society (2023 – present)
• Young Organic Chemist Award at KCS Organic Chemistry Division 2022
• Thieme Chemistry Journal Awards 2020
• Outstanding Scientific Achievement, Max-Planck-Institut, Germany, Dec 2017
• Stipendium 350, Max-Planck-Institut, Germany, Sep 2015 – Apr 2016
• Award for Best Ph.D. Thesis (대한화학회 우수박사학위 논문상), Korean Chemical Society, Korea, Oct 2015
• Valedictorian (졸업생 대표답사), Sungkyunkwan University, Korea, Aug 2015
• DOW Chemical Scholarship, DOW Chemical, Korea, Feb 2015
• Chemical Science Presentation Award, Royal Chemical Society, UK, Dec 2014
• Academic Excellence Scholarship, Sungkyunkwan University, Korea, 2012 – 2013
• Best Presentation Award, Organic Chemistry Division of KCS, Aug 2013
• Brain Korea 21 Scholarship, Ministry of Education, Korea, Mar 2010 – Feb 2012
• Best Presentation Award, Korean Chemical Society (KCS), Oct 2012
• Best Publication Award, Ewha Womans University, Korea, Feb 2012
• Best Presentation Award, Brain Korea 21 Symposium, Korea, Feb 2012
• Academic Excellence Scholarship, Sungkyunkwan University, Korea, 2004 and 2009
REPRESENTATIVE PUBLICATIONS
"“On-Water” Accelerated Dearomative Cycloaddition via Aquaphotocatalysis"
S. B. Kim, D. H. Kim, H. Y. Bae
Nature Communications 2024, 15, 3876.
"Water-accelerated single-electron transfer aquaphotocatalysis for open-chain SuFEx hubs"
B. J. Koo, Y. Kwon, A. H. Son, D. H. Kim, S. B. Kim, S. Kim, W. Jeon, M. S. Kwon,* H. Y. Bae*
Cell Reports Physical Science 2024, 5, 102279.
"Pinacolborane-assisted superacid organocatalysis enabled direct access to cytotoxic alkyl N-Cbz amines"
W. H. Kim, S. B. Song, D. E. Lee, P. Goswami, Y. K. Chung, S. Choi, W. H. Jung, S. U. Choi, S. Ham, Y. Oh, K. H. Kim, J. Huh, H. Y. Bae
Cell Reports Physical Science 2024, 5, 101786
"Sustainable Organocatalytic Cyanosilylation of Ketones by PPM-Level Loading Triphenylcarbenium Tetrakis(pentafluorophenyl)borate"
M. Israr, H. Y. Bae
Green Chemistry 2023, 25, 2387
"Efficient Access to General α-Tertiary Amines via Water-Accelerated Organocatalytic Multicomponent Allylation"
P. Goswami, S. Y. Cho, J. H. Park, W. H. Kim, H. J. Kim, M. H. Shin, H. Y. Bae
Nature Communications 2022, 13, 2702
"Organocatalytic Stereoselective Cyanosilylation of Small Ketones"
H. Zhou, Y. Zhou, H. Y. Bae, M. Leutzsch, Y. Li, C. K. De, G. Cheng, B. List
Nature 2022, 605, 84.
"N-Triflyl Phosphoric Triamide: A High-Performance Purely Organic Trifurcate Quartz Crystal Microbalance Sensor for Chemical Warfare Agent"
J. H. Park, S. G. Song, M. H. Shin,† C. Song, H. Y. Bae
ACS Sensors 2022. 7, 423.
[Patent issued: 1 Apr. 2024 (N-TPT derivatives and their synthetic process)]
"Approaching sub-ppm level asymmetric organocatalysis of a highly challenging and scalable carbon–carbon bond forming reaction"
H. Y. Bae, D. Höfler, P. S. J. Kaib, P. Kasaplar, C. K. De, A. Döhring, S. Lee, K. Kaupmees, I. Leito, B. List
Nature Chemistry 2018, 10, 888.
"Triflimide: An overlooked high-performance catalyst of the Mukaiyama aldol reaction of silyl ketene acetals with ketones"
H. Y. Bae, S. Lee, B. List
Chemistry – A European Journal 2018, 24, 13767.
"Direct catalytic asymmetric Mannich reaction with dithiomalonate as an excellent donor: the first organocatalytic synthesis of (R)-Sitagliptin"
H. Y. Bae, M. J. Kim, J. H. Sim, C. E. Song
Angewandte Chemie International Edition 2016, 55, 10825.
[Patent issued: 20 Jun. 2018 (the process of primary alkyl mannich reaction)]
[Patent issued: 20 Mar. 2019 (the process of total synthesis toward antidiabetic drug Sitagliptin and its intermediate)]
"Unprecedented hydrophobic amplification in noncovalent organocatalysis "on water": Hydrophobic chiral squaramide catalyzed Michael addition of malonates to nitroalkenes"
H. Y. Bae, C. E. Song
ACS Catalysis 2015, 5, 3613.
[Patent issued: 25 Aug. 2015 (the process of total synthesis toward anticonvulsant drug Pregabalin)]
[Patent issued: 25 Aug. 2015 (the process of total synthesis toward selective phosphodiesterase-4 inhibitor Rolipram)]
"Organocatalytic enantioselective decarboxylative aldol reaction of malonic acid half thioesters to aldehydes"
H. Y. Bae, J. H. Sim, J. W. Lee, B. List, C. E. Song
Angewandte Chemie International Edition 2013, 52, 12143.
[Patent issued: 19 Nov. 2014 (the first organocatalytic decarboxylative aldol reaction of MAHTs)]